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Efficient Synthesis of 3H-Indoles Enabled by the Lead-Mediated α-Arylation of β-Ketoesters or γ-Lactams Using Aryl Azides

[Image: see text] The development of a lead-mediated α-arylation reaction between aryl azides and β-ketoesters or γ-lactams that facilitates the formation of 3H-indoles is disclosed. Twenty-five examples are included which demonstrate the generality of this reaction to access aryl azides bearing tet...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhou, Fei, Driver, Tom G.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2014
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059265/
https://ncbi.nlm.nih.gov/pubmed/24865180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol5010615
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