Recognition and killing of autologous, primary glioblastoma tumor cells by human cytomegalovirus pp65-specific cytotoxic T cells

PURPOSE: Despite aggressive conventional therapy, glioblastoma multiforme (GBM) remains uniformly lethal. Immunotherapy, in which the immune system is harnessed to specifically attack malignant cells, offers a treatment option with less toxicity. The expression of cytomegalovirus (CMV) antigens in G...

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Detalhes bibliográficos
Main Authors: Nair, Smita K., De Leon, Gabriel, Boczkowski, David, Schmittling, Robert, Xie, Weihua, Staats, Janet, Liu, Rebecca, Johnson, Laura A., Weinhold, Kent, Archer, Gary E., Sampson, John H., Mitchell, Duane A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059212/
https://ncbi.nlm.nih.gov/pubmed/24658154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3268
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