Protein Phosphatase 2A (PP2A) Regulates Low Density Lipoprotein Uptake through Regulating Sterol Response Element-binding Protein-2 (SREBP-2) DNA Binding

LDL-cholesterol (LDL-C) uptake by Ldlr is regulated at the transcriptional level by the cleavage-dependent activation of membrane-associated sterol response element-binding protein (SREBP-2). Activated SREBP-2 translocates to the nucleus, where it binds to an LDLR promoter sterol response element (S...

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Bibliografische gegevens
Hoofdauteurs: Rice, Lyndi M., Donigan, Melissa, Yang, Muhua, Liu, Weidong, Pandya, Devanshi, Joseph, Biny K., Sodi, Valerie, Gearhart, Tricia L., Yip, Jenny, Bouchard, Michael, Nickels, Joseph T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
Onderwerpen:
Lipids
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059166/
https://ncbi.nlm.nih.gov/pubmed/24770487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.570390
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