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Expression of the Yeast Cation Diffusion Facilitators Mmt1 and Mmt2 Affects Mitochondrial and Cellular Iron Homeostasis: EVIDENCE FOR MITOCHONDRIAL IRON EXPORT

Mmt1 and Mmt2 are highly homologous yeast members of the cation diffusion facilitator transporter family localized to mitochondria. Overexpression of MMT1/2 led to changes in cellular metal homeostasis (increased iron sensitivity, decreased cobalt sensitivity, increased sensitivity to copper), oxida...

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Main Authors: Li, Liangtao, Miao, Ren, Jia, Xuan, Ward, Diane M., Kaplan, Jerry
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059154/
https://ncbi.nlm.nih.gov/pubmed/24798331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574723
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