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Non-repair Pathways for Minimizing Protein Isoaspartyl Damage in the Yeast Saccharomyces cerevisiae

The spontaneous degradation of asparaginyl and aspartyl residues to isoaspartyl residues is a common type of protein damage in aging organisms. Although the protein-l-isoaspartyl (d-aspartyl) O-methyltransferase (EC 2.1.1.77) can initiate the repair of l-isoaspartyl residues to l-aspartyl residues i...

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Detalhes bibliográficos
Main Authors: Patananan, Alexander N., Capri, Joseph, Whitelegge, Julian P., Clarke, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059137/
https://ncbi.nlm.nih.gov/pubmed/24764295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.564385
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