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Transgene-mediated co-suppression of DNA topoisomerase-1 gene in Caenorhabditis elegans

Ectopic expression of multi-transgenic copies can result in reduced expression of the transgene and can induce silence of endogenous gene; this process is called as co-suppression. Using a transgene-mediated co-suppression technique, we demonstrated the biological function of DNA topoisomerase-1 (to...

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Autors principals: Lee, Myon-Hee, Cha, Dong Seok, Mamillapalli, Srivalli Swathi, Kwon, Young Chul, Koo, Hyeon-Sook
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058960/
https://ncbi.nlm.nih.gov/pubmed/24955284
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