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Transgene-mediated co-suppression of DNA topoisomerase-1 gene in Caenorhabditis elegans

Ectopic expression of multi-transgenic copies can result in reduced expression of the transgene and can induce silence of endogenous gene; this process is called as co-suppression. Using a transgene-mediated co-suppression technique, we demonstrated the biological function of DNA topoisomerase-1 (to...

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Hlavní autoři: Lee, Myon-Hee, Cha, Dong Seok, Mamillapalli, Srivalli Swathi, Kwon, Young Chul, Koo, Hyeon-Sook
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058960/
https://ncbi.nlm.nih.gov/pubmed/24955284
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