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New directions for diffusion-based network prediction of protein function: incorporating pathways with confidence

Motivation: It has long been hypothesized that incorporating models of network noise as well as edge directions and known pathway information into the representation of protein–protein interaction (PPI) networks might improve their utility for functional inference. However, a simple way to do this h...

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Detalhes bibliográficos
Main Authors: Cao, Mengfei, Pietras, Christopher M., Feng, Xian, Doroschak, Kathryn J., Schaffner, Thomas, Park, Jisoo, Zhang, Hao, Cowen, Lenore J., Hescott, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058952/
https://ncbi.nlm.nih.gov/pubmed/24931987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu263
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