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Tertiary structure-based prediction of conformational B-cell epitopes through B factors

Motivation: B-cell epitope is a small area on the surface of an antigen that binds to an antibody. Accurately locating epitopes is of critical importance for vaccine development. Compared with wet-lab methods, computational methods have strong potential for efficient and large-scale epitope predicti...

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Bibliographic Details
Main Authors: Ren, Jing, Liu, Qian, Ellis, John, Li, Jinyan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058920/
https://ncbi.nlm.nih.gov/pubmed/24931993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu281
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