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Ligand induced dynamics changes in extended PDZ domains from NHERF1
The multi-domain scaffolding protein NHERF1 modulates the assembly and intracellular trafficking of various transmembrane receptors and ion-transport proteins. The two PDZ domains of NHERF1 possess very different ligand-binding capabilities: PDZ1 recognizes a variety of membrane proteins with high a...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058784/ https://ncbi.nlm.nih.gov/pubmed/23583913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.001 |
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