Raf-1 oncogenic signaling is linked to activation of mesenchymal to epithelial transition pathway in metastatic breast cancer cells

Aberrant activation of the Raf/MEK/MAPK pathway plays a key role in breast cancer development and progression. Dysregulation of Raf/MEK/MAPK oncogenic signaling often results from overexpression of the HER-2/Neu tyrosine kinase receptor leading to chemoendocrine resistance, development of distant me...

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Päätekijät: LEONTOVICH, ALEXEY A., ZHANG, SHUYA, QUATRARO, COSIMA, IANKOV, IANKO, VEROUX, PIER FRANCESCO, GAMBINO, MARIO W., DEGNIM, AMY, McCUBREY, JAMES, INGLE, JAMES, GALANIS, EVANTHIA, D'ASSORO, ANTONINO B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058770/
https://ncbi.nlm.nih.gov/pubmed/22447278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1407
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