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Mechanism and rates of exchange of L7/L12 between ribosomes and the effects of binding EF–G

The ribosomal stalk complex binds and recruits translation factors to the ribosome during protein biosynthesis. In Escherichia coli the stalk is composed of protein L10 and four copies of L7/L12. Despite the crucial role of the stalk, mechanistic details of L7/L12 subunit exchange are not establishe...

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Autores principales: Deroo, Stéphanie, Hyung, Suk-Joon, Marcoux, Julien, Gordiyenko, Yuliya, Koripella, Ravi Kiran, Sanyal, Suparna, Robinson, Carol V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058753/
https://ncbi.nlm.nih.gov/pubmed/22489843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300081s
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