Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G

The ribosomal stalk in bacteria is composed of four or six copies of L12 proteins arranged in dimers that bind to the adjacent sites on protein L10, spanning 10 amino acids each from the L10 C-terminus. To study why multiple L12 dimers are required on the ribosome, we created a chromosomally enginee...

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Bibliographic Details
Main Authors: Mandava, Chandra Sekhar, Peisker, Kristin, Ederth, Josefine, Kumar, Ranjeet, Ge, Xueliang, Szaflarski, Witold, Sanyal, Suparna
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299993/
https://ncbi.nlm.nih.gov/pubmed/22102582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1031
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