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Trastuzumab emtansine: mechanisms of action and drug resistance

Trastuzumab emtansine (T-DM1) is an antibody-drug conjugate that is effective and generally well tolerated when administered as a single agent to treat advanced breast cancer. Efficacy has now been demonstrated in randomized trials as first line, second line, and later than the second line treatment...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Barok, Mark, Joensuu, Heikki, Isola, Jorma
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058749/
https://ncbi.nlm.nih.gov/pubmed/24887180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3621
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