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Trastuzumab emtansine: mechanisms of action and drug resistance
Trastuzumab emtansine (T-DM1) is an antibody-drug conjugate that is effective and generally well tolerated when administered as a single agent to treat advanced breast cancer. Efficacy has now been demonstrated in randomized trials as first line, second line, and later than the second line treatment...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058749/ https://ncbi.nlm.nih.gov/pubmed/24887180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3621 |
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