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Trastuzumab: updated mechanisms of action and resistance in breast cancer
HER2-postitive breast cancer has the second-poorest prognosis among breast cancer subtypes. One of the most effective targeted therapies for patients with HER2-positive breast cancer is trastuzumab-based. However, primary or acquired resistance to trastuzumab has been a major obstacle in the clinica...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2012-06-01
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Colecção: | Frontiers in Oncology |
Assuntos: | |
Acesso em linha: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00062/full |
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