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Synthesis and Biological Screening of 4-Benzyl-2H-phthalazine Derivatives

Preparation of 4-benzyl-2-substituted phthalazin-1-one derivatives 2-8 is reported. Condensation of 4-benzyl-1-chlorophthalazine (9) with a series of different nucleophiles gave 4-benzylphthalazin-1-ylamino derivatives (10-13 and 16) and 4-amino-2-[N′-(4-benzylphthalazin-1-yl)-hydrazino]-6-arylpyrim...

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Detalhes bibliográficos
Main Authors: El-Wahab, Ashraf H.F. Abd, Mohamed, Hany M., El-Agrody, Ahmed M., El-Nassag, Mohammed A., Bedair, Ahmed H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058664/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph4081158
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