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Synthesis and characterization of new diiodocoumarin derivatives with promising antimicrobial activities

A series of 6,8-diiodocoumarin-3-N-carboxamides (4–11) were prepared. Treatment of ethyl 6,8-diiodocoumarin-3-carboxylate (1) with ethyl cyanoacetate/NH(4)OAc gave ethyl 2-(3-carbamoyl-6,8-diiodocoumarin-4-yl)-2-cyanoacetate (12) and 2-amino-4-hydroxy-7,9-diiodocoumarino[3,4-c]pyridine-1-carbonitril...

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Detalhes bibliográficos
Main Authors: Mohamed, Hany M, EL-Wahab, Ashraf H F Abd, EL-Agrody, Ahmed M, Bedair, Ahmed H, Eid, Fathy A, Khafagy, Mostafa M, Abd-EL-Rehem, Kamal A
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252874/
https://ncbi.nlm.nih.gov/pubmed/22238548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.199
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