Vascular tone pathway polymorphisms in relation to primary open-angle glaucoma

AIMS: Vascular perfusion may be impaired in primary open-angle glaucoma (POAG); thus, we evaluated a panel of markers in vascular tone-regulating genes in relation to POAG. METHODS: We used Illumina 660W-Quad array genotype data and pooled P-values from 3108 POAG cases and 3430 controls from the com...

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Autori principali: Kang, J H, Loomis, S J, Yaspan, B L, Bailey, J C, Weinreb, R N, Lee, R K, Lichter, P R, Budenz, D L, Liu, Y, Realini, T, Gaasterland, D, Gaasterland, T, Friedman, D S, McCarty, C A, Moroi, S E, Olson, L, Schuman, J S, Singh, K, Vollrath, D, Wollstein, G, Zack, D J, Brilliant, M, Sit, A J, Christen, W G, Fingert, J, Forman, J P, Buys, E S, Kraft, P, Zhang, K, Allingham, R R, Pericak-Vance, M A, Richards, J E, Hauser, M A, Haines, J L, Wiggs, J L, Pasquale, L R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058608/
https://ncbi.nlm.nih.gov/pubmed/24603425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2014.42
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