Olmesartan Attenuates Tacrolimus-Induced Biochemical and Ultrastructural Changes in Rat Kidney Tissue

Tacrolimus, a calcineurin inhibitor, is clinically used as an immunosuppressive agent in organ transplantation, but its use is limited due to its marked nephrotoxicity. The present study investigated the effect of olmesartan (angiotensin receptor blocker) on tacrolimus-induced nephrotoxicity in rats...

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Autors principals: Al-Harbi, Naif O., Imam, Faisal, Al-Harbi, Mohammed M., Iqbal, Muzaffar, Nadeem, Ahmed, Sayed-Ahmed, Mohammed M., Alabidy, Ali D., Almukhallafi, Ali F.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058524/
https://ncbi.nlm.nih.gov/pubmed/24987695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/607246
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