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Molecular Mechanisms of Bone Metastasis and Associated Muscle Weakness

Bone is a preferred site for breast cancer metastasis and leads to pathological bone loss due to increased osteoclast-induced bone resorption. The homing of tumor cells to the bone depends on the support of the bone microenvironment in which the tumor cells prime the pre-metastatic niche. The coloni...

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Detalhes bibliográficos
Main Authors: Waning, David L., Guise, Theresa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058425/
https://ncbi.nlm.nih.gov/pubmed/24677373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1590
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