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TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis

Urinary bladder pain is a primary symptom associated with interstitial cystitis/painful bladder syndrome. We employed systemic injections of cyclophosphamide (CYP), an alkylating anti-neoplastic agent, to induce cystitis and examine the roles of two channels previously shown to be required for infla...

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Autori principali: DeBerry, Jennifer J., Schwartz, Erica S., Davis, Brian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058378/
https://ncbi.nlm.nih.gov/pubmed/24704367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2014.03.023
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