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Artemin immunotherapy is effective in preventing and reversing cystitis-induced bladder hyperalgesia via TRPA1 regulation
Injury- or disease-induced artemin (ARTN) signaling can sensitize primary afferents and contribute to persistent pain. We demonstrate that administration of an anti-artemin (α-ARTN) neutralizing antibody can block the development of, and reverse already established, bladder hyperalgesia associated w...
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| Publicado no: | J Pain |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489144/ https://ncbi.nlm.nih.gov/pubmed/25892657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2015.03.014 |
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