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Genome-wide transcriptome analyses reveals p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumors

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue tumors that occur either sporadically or in patients with Neurofibromatosis Type 1. The malignant transformation of the benign neurofibroma to MPNST is incompletely understood at the molecular level. We have determined the...

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Detalhes bibliográficos
Main Authors: Subramanian, Subbaya, Thayanithy, Venugopal, West, Robert B., Lee, Cheng-Han, Beck, Andrew H., Zhu, Shirley, Downs-Kelly, Erinn, Montgomery, Kelli, Goldblum, John R., Hogendoorn, Pancras C.W., Corless, Christopher L., Oliveira, Andre M., Dry, Sarah M., Nielsen, Torsten O., Rubin, Brian P., Fletcher, Jonathan A., Fletcher, Christopher D.M., van de Rijn, Matt
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058327/
https://ncbi.nlm.nih.gov/pubmed/19890883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2633
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