The Early Activation of CD8(+) T Cells Is Dependent on Type I IFN Signaling following Intramuscular Vaccination of Adenovirus Vector

Few of the vaccines in current use can induce antigen- (Ag-) specific immunity in both mucosal and systemic compartments. Hence, the development of vaccines that realize both mucosal and systemic protection against various pathogens is a high priority in global health. Recently, it has been reported...

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Autors principals: Hemmi, Masahisa, Tachibana, Masashi, Tsuzuki, Sayaka, Shoji, Masaki, Sakurai, Fuminori, Kawabata, Kenji, Kobiyama, Kouji, Ishii, Ken J., Akira, Shizuo, Mizuguchi, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058243/
https://ncbi.nlm.nih.gov/pubmed/24971314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/158128
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