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Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells

Interchromosomal associations can regulate gene expression but little is known about the molecular basis of such associations. In response to antigen stimulation, naïve T cells can differentiate into Th1, Th2 and Th17 cells expressing IFN-γ, IL-4 and IL-17, respectively. We previously reported that...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Lark Kyun, Esplugues, Enric, Zorca, Cornelia E., Galjart, Niels J., Flavell, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058095/
https://ncbi.nlm.nih.gov/pubmed/24613343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.02.004
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