ロード中...

SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines

OBJECTIVES: Primary and acquired resistance to EGFR TKIs in EGFR mutant lung cancer occurs primarily through secondary mutations in EGFR or Met amplification. Drug resistance can also be mediated by expression of pluripotency transcription factors, such as OCT4, SOX2 and NANOG that decrease terminal...

詳細記述

保存先:
書誌詳細
主要な著者: Dogan, Irem, Kawabata, Shigeru, Bergbower, Emily, Gills, Joell J., Ekmekci, Abdullah, Wilson, Willie, Rudin, Charles M., Dennis, Phillip A.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058091/
https://ncbi.nlm.nih.gov/pubmed/24746758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2014.03.021
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!