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Aggresome formation is regulated by RanBPM through an interaction with HDAC6

In conditions of proteasomal impairment, the build-up of damaged or misfolded proteins activates a cellular response leading to the recruitment of damaged proteins into perinuclear aggregates called aggresomes. Aggresome formation involves the retrograde transport of cargo proteins along the microtu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Salemi, Louisa M., Almawi, Ahmad W., Lefebvre, Karen J., Schild-Poulter, Caroline
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058076/
https://ncbi.nlm.nih.gov/pubmed/24795145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147021
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