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Aggresome formation is regulated by RanBPM through an interaction with HDAC6
In conditions of proteasomal impairment, the build-up of damaged or misfolded proteins activates a cellular response leading to the recruitment of damaged proteins into perinuclear aggregates called aggresomes. Aggresome formation involves the retrograde transport of cargo proteins along the microtu...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058076/ https://ncbi.nlm.nih.gov/pubmed/24795145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147021 |
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