Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice

Tumor blood vessels are leaky and immature, which causes inadequate blood supply to tumor tissues resulting in hypoxic microenvironment and promotes metastasis. Here we have explored tumor vessel modulating activity of Sac-1004, a recently developed molecule in our lab, which directly potentiates VE...

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Bibliografiske detaljer
Main Authors: Agrawal, Vijayendra, Maharjan, Sony, Kim, Kyeojin, Kim, Nam-Jung, Son, Jimin, Lee, Keunho, Choi, Hyun-Jung, Rho, Seung-Sik, Ahn, Sunjoo, Won, Moo-Ho, Ha, Sang-Jun, Koh, Gou Young, Kim, Young-Myeong, Suh, Young-Ger, Kwon, Young-Guen
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058043/
https://ncbi.nlm.nih.gov/pubmed/24811731
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