ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples

Astrocytic tumors are the most common primary brain tumors in adults. ATRX mutations have been identified in gliomas and are correlated with its loss of expression, which causes alternative lengthening of telomeres (ALT) leading to genomic instability. In this study, we aimed to explore the role of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cai, Jinquan, Yang, Pei, Zhang, Chuanbao, Zhang, Wei, Liu, Yanwei, Bao, Zhaoshi, Liu, Xing, Du, Wenzhong, Wang, Hongjun, Jiang, Tao, Jiang, Chuanlu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2014
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058026/
https://ncbi.nlm.nih.gov/pubmed/24810474
Tagiau: Ychwanegu Tag
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