Bak and Mcl-1 are essential for Temozolomide induced cell death in human glioma

Temozolomide (TMZ) is an alkylating agent used for the treatment of glioblastoma multiforme (GBM), the main form of human brain tumours in adults. It has been reported that TMZ induced DNA lesions that subsequently trigger cell death but the actual mechanisms involved in the process are still unclea...

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Detaylı Bibliyografya
Asıl Yazarlar: Gratas, Catherine, Séry, Quentin, Rabé, Marion, Oliver, Lisa, Vallette, François M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2014
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058016/
https://ncbi.nlm.nih.gov/pubmed/24811082
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