HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1

BACKGROUND: The Vpr protein of human immunodeficiency virus type 1 (HIV-1) plays an important role in viral replication. It has been reported that Vpr stimulates the nuclear factor-κB (NF-κB) and activator protein 1 (AP-1) signaling pathways, and thereby regulates viral and host cell gene expression...

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Detalhes bibliográficos
Main Authors: Liu, Ruikang, Lin, Yongquan, Jia, Rui, Geng, Yunqi, Liang, Chen, Tan, Juan, Qiao, Wentao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057933/
https://ncbi.nlm.nih.gov/pubmed/24912525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-45
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