Efficacy of novel antibacterial compounds targeting histidine kinase YycG protein

Treating staphylococcal biofilm-associated infections is challenging. Based on the findings that compound 2 targeting the HK domain of Staphylococcus epidermidis YycG has bactericidal and antibiofilm activities against staphylococci, six newly synthesized derivatives were evaluated for their antibac...

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Bibliographic Details
Main Authors: Liu, Huayong, Zhao, Dan, Chang, Jun, Yan, Liang, Zhao, Fuju, Wu, Youcong, Xu, Tao, Gong, Ting, Chen, Li, He, Nianan, Wu, Yang, Han, Shiqing, Qu, Di
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2014
Subjects:
Applied Genetics and Molecular Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057637/
https://ncbi.nlm.nih.gov/pubmed/24737057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-014-5685-8
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