Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA- a randomized multicenter phase III study (NCT01900327, DRKS00003893, ISRCTN82191749)

BACKGROUND: Median OS after surgery in curative intent for non-metastasized pancreas cancer ranges under study conditions from 17.9 months to 23.6 months. Tumor recurrence occurs locally, at distant sites (liver, peritoneum, lungs), or both. Observational and autopsy series report local recurrence r...

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Bibliographic Details
Main Authors: Tachezy, Michael, Gebauer, Florian, Petersen, Cordula, Arnold, Dirk, Trepel, Martin, Wegscheider, Karl, Schafhausen, Phillipe, Bockhorn, Maximilian, Izbicki, Jakob Robert, Yekebas, Emre
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Study Protocol
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057592/
https://ncbi.nlm.nih.gov/pubmed/24906700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-411
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