Imaging genomic mapping of an invasive MRI phenotype predicts patient outcome and metabolic dysfunction: a TCGA glioma phenotype research group project

BACKGROUND: Invasion of tumor cells into adjacent brain parenchyma is a major cause of treatment failure in glioblastoma. Furthermore, invasive tumors are shown to have a different genomic composition and metabolic abnormalities that allow for a more aggressive GBM phenotype and resistance to therap...

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Détails bibliographiques
Auteurs principaux: Colen, Rivka R, Vangel, Mark, Wang, Jixin, Gutman, David A, Hwang, Scott N, Wintermark, Max, Jain, Rajan, Jilwan-Nicolas, Manal, Chen, James Y, Raghavan, Prashant, Holder, Chad A, Rubin, Daniel, Huang, Eric, Kirby, Justin, Freymann, John, Jaffe, Carl C, Flanders, Adam, Zinn, Pascal O
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057583/
https://ncbi.nlm.nih.gov/pubmed/24889866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-30
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