Inhibition of the inflammatory cytokine tumor necrosis factor-alpha with etanercept provides protection against lethal H1N1 influenza infection in mice

INTRODUCTION: Factors implicated in influenza-mediated morbidity and mortality include robust cytokine production (cytokine storm), excessive inflammatory infiltrates, and virus-induced tissue destruction. Tumor necrosis factor-alpha (TNF-α) is an important pro-inflammatory cytokine present during i...

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Hlavní autoři: Shi, Xunlong, Zhou, Wei, Huang, Hai, Zhu, Hongguang, Zhou, Pei, Zhu, Haiyan, Ju, Dianwen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057515/
https://ncbi.nlm.nih.gov/pubmed/24373231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13171
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