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PEGylated human catalase elicits potent therapeutic effects on H1N1 influenza-induced pneumonia in mice
Therapeutic recombinant human catalase (rhCAT) can quench infection-induced reactive oxygen species (ROS), thereby alleviating the associated tissue damage. Although the intranasal route is efficient to deliver native rhCAT to the lung, the therapeutic effect is limited by rapid elimination from the...
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| Udgivet i: | Appl Microbiol Biotechnol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7079947/ https://ncbi.nlm.nih.gov/pubmed/23525936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-013-4775-3 |
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