High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria

INTRODUCTION: The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections. Many concerns have been raised about the efficacy of this molecule and increased dosages have been propos...

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Autori principali: De Pascale, Gennaro, Montini, Luca, Pennisi, Mariano Alberto, Bernini, Valentina, Maviglia, Riccardo, Bello, Giuseppe, Spanu, Teresa, Tumbarello, Mario, Antonelli, Massimo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057423/
https://ncbi.nlm.nih.gov/pubmed/24887101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13858
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