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VALSARTAN REGULATES MYOCARDIAL AUTOPHAGY AND MITOCHONDRIAL TURNOVER IN EXPERIMENTAL HYPERTENSION

Renovascular hypertension alters cardiac structure and function. Autophagy is activated during left ventricular hypertrophy and linked to adverse cardiac function. The Angiotensin II receptor blocker Valsartan lowers blood pressure and is cardioprotective, but whether it modulates autophagy in the m...

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Autores principales: Zhang, Xin, Li, Zi-Lun, Crane, John A., Jordan, Kyra L., Pawar, Aditya S., Textor, Stephen C., Lerman, Amir, Lerman, Lilach O.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057304/
https://ncbi.nlm.nih.gov/pubmed/24752430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02151
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