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Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity

INTRODUCTION: Sepsis is characterized by systemic immune activation and neutrophil-mediated endothelial barrier integrity compromise, contributing to end-organ dysfunction. Studies evaluating endothelial barrier dysfunction induced by neutrophils from septic patients are lacking, despite its clinica...

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Autori principali: Fox, Elizabeth D, Heffernan, Daithi S, Cioffi, William G, Reichner, Jonathan S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057230/
https://ncbi.nlm.nih.gov/pubmed/24099563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13049
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