Low plasma citrulline levels are associated with acute respiratory distress syndrome in patients with severe sepsis

INTRODUCTION: The role of nitric oxide synthase (NOS) in the pathophysiology of acute respiratory distress syndrome (ARDS) is not well understood. Inducible NOS is upregulated during physiologic stress; however, if NOS substrate is insufficient then NOS can uncouple and switch from NO generation to...

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Detalhes bibliográficos
Main Authors: Ware, Lorraine B, Magarik, Jordan A, Wickersham, Nancy, Cunningham, Gary, Rice, Todd W, Christman, Brian W, Wheeler, Arthur P, Bernard, Gordon R, Summar, Marshall L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056746/
https://ncbi.nlm.nih.gov/pubmed/23327349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc11934
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