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Antigenic Variation of Clade 2.1 H5N1 Virus Is Determined by a Few Amino Acid Substitutions Immediately Adjacent to the Receptor Binding Site
Highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype are genetically highly variable and have diversified into multiple phylogenetic clades over the past decade. Antigenic drift is a well-studied phenomenon for seasonal human influenza viruses, but much less is known about the antige...
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Główni autorzy: | , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society of Microbiology
2014
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056550/ https://ncbi.nlm.nih.gov/pubmed/24917596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01070-14 |
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