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Isotype Switching Increases Efficacy of Antibody Protection against Staphylococcal Enterotoxin B-Induced Lethal Shock and Staphylococcus aureus Sepsis in Mice

Staphylococcal enterotoxin B (SEB) is a potent toxin that is produced by Staphylococcus aureus strains and is classified as a category B select agent. We have previously shown that monoclonal antibody (MAb) 20B1, a murine anti-SEB IgG1, successfully treats SEB-induced lethal shock (SEBILS) and bacte...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Varshney, Avanish K., Wang, Xiaobo, Aguilar, Jorge L., Scharff, Matthew D., Fries, Bettina C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Microbiology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056548/
https://ncbi.nlm.nih.gov/pubmed/24917594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01007-14
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