A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection

Numerous high-throughput sequencing studies have focused on detecting conventionally spliced mRNAs in RNA-seq data. However, non-standard RNAs arising through gene fusion, circularization or trans-splicing are often neglected. We introduce a novel, unbiased algorithm to detect splice junctions from...

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Detalhes bibliográficos
Main Authors: Hoffmann, Steve, Otto, Christian, Doose, Gero, Tanzer, Andrea, Langenberger, David, Christ, Sabina, Kunz, Manfred, Holdt, Lesca M, Teupser, Daniel, Hackermüller, Jörg, Stadler, Peter F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056463/
https://ncbi.nlm.nih.gov/pubmed/24512684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-2-r34
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