Differential protein occupancy profiling of the mRNA transcriptome

BACKGROUND: RNA-binding proteins (RBPs) mediate mRNA biogenesis, translation and decay. We recently developed an approach to profile transcriptome-wide RBP contacts on polyadenylated transcripts by next-generation sequencing. A comparison of such profiles from different biological conditions has the...

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Bibliografiske detaljer
Main Authors: Schueler, Markus, Munschauer, Mathias, Gregersen, Lea Haarup, Finzel, Ana, Loewer, Alexander, Chen, Wei, Landthaler, Markus, Dieterich, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056462/
https://ncbi.nlm.nih.gov/pubmed/24417896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-1-r15
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