Computational inference of mRNA stability from histone modification and transcriptome profiles

Histone modifications play important roles in regulating eukaryotic gene expression and have been used to model expression levels. Here, we present a regression model to systematically infer mRNA stability by comparing transcriptome profiles with ChIP-seq of H3K4me3, H3K27me3 and H3K36me3. The resul...

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Detalhes bibliográficos
Main Authors: Wang, Chengyang, Tian, Rui, Zhao, Qian, Xu, Han, Meyer, Clifford A., Li, Cheng, Zhang, Yong, Liu, X. Shirley
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Computational Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413115/
https://ncbi.nlm.nih.gov/pubmed/22495509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks304
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