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RIDDLE: reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network

The growing availability of large-scale functional networks has promoted the development of many successful techniques for predicting functions of genes. Here we extend these network-based principles and techniques to functionally characterize whole sets of genes. We present RIDDLE (Reflective Diffu...

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Autori principali: Wang, Peggy I, Hwang, Sohyun, Kincaid, Rodney P, Sullivan, Christopher S, Lee, Insuk, Marcotte, Edward M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056375/
https://ncbi.nlm.nih.gov/pubmed/23268829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-12-r125
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