Kinetics and protective role of autophagy in a mouse cecal ligation and puncture-induced sepsis

INTRODUCTION: It is not well understood whether the process of autophagy is accelerated or blocked in sepsis, and whether it is beneficial or harmful to the immune defense mechanism over a time course during sepsis. Our aim was to determine both the kinetics and the role of autophagy in sepsis. METH...

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Main Authors: Takahashi, Waka, Watanabe, Eizo, Fujimura, Lisa, Watanabe-Takano, Haruko, Yoshidome, Hiroyuki, Swanson, Paul E, Tokuhisa, Takeshi, Oda, Shigeto, Hatano, Masahiko
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056358/
https://ncbi.nlm.nih.gov/pubmed/23883625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc12839
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