Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice

Experimental sepsis can be induced in mice using the cecal ligation and puncture (CLP) method, which causes polymicrobial sepsis. Here, a protocol is provided to induce sepsis of varying severity in mice using the CLP technique. Autophagy is a fundamental tissue response to stress and pathogen invas...

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Main Authors: Siempos, Ilias I., Lam, Hilaire C., Ding, Yan, Choi, Mary E., Choi, Augustine M. K., Ryter, Stefan W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MyJove Corporation 2014
Ábhair:
Infection
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122027/
https://ncbi.nlm.nih.gov/pubmed/24561344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51066
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