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A Role for Retrotransposon LINE-1 in Fetal Oocyte Attrition in Mice
Fetal oocyte attrition (FOA) is a conserved but poorly understood process of elimination of over two-thirds of meiotic prophase I (MPI) oocytes before birth. We now implicate retrotransposons LINE-1 (L1), activated during epigenetic reprogramming of the embryonic germline, in FOA in mice. We show th...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056315/ https://ncbi.nlm.nih.gov/pubmed/24882376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.027 |
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